Barnaviridae
| Barnaviridae | |
|---|---|
| |
| Barnavirus virion | |
| |
| Barnavirus genome | |
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Sobelivirales |
| Family: | Barnaviridae |
Barnaviridae is a family of non-enveloped, positive-strand RNA viruses. Cultivated mushrooms serve as natural hosts. The family has one genus, Barnavirus, which contains one species: Mushroom bacilliform virus. Diseases associated with this family includes La France disease.[1][2]
Structure
[edit]Viruses in Barnaviridae are non-enveloped, with icosahedral and Bacilliform geometries, and T=1 symmetry. These viruses are about 50 nm long.[citation needed]
Genome
[edit]Genomes are linear, around 4kb in length. The genome has 4 open reading frames. Genomic RNA serves as both the genome and viral messenger RNA. ORF2 is a polyprotein which is possibly auto-cleaved by the ORF2 viral protease. ORF3 encodes the RNA dependent RNA polymerase and may be translated by ribosomal frameshifting as an ORF2-ORF3 polyprotein. The single capsid protein (ORF4) is translated from a subgenomic RNA.[1]
Life cycle
[edit]Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell and passing it down. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. The virus is released horizontal via mycelium and basidiospores. Cultivated mushroom, Agaricus bisporus, serves as the natural host.[1]
References
[edit]- ^ a b c "Viral Zone". ExPASy. Retrieved 12 June 2015.
- ^ "Virus Taxonomy: 2022 Release". International Committee on Taxonomy of Viruses (ICTV). March 2023. Retrieved 10 August 2023.